California Cancer Reporting System Standards Volume I: Abstracting and Coding Procedures
The Mets at Diagnosis – Brain data item captures whether the brain is an involved metastatic site at the time of diagnosis.
Code information about brain metastasis only (discontinuous or distant) to the brain identified at the time of diagnosis.
NOTE: Spinal cord involvement is NOT coded in this field. See Mets at Diagnosis – Other.
Metastatic involvement may be single (one focus of metastatic disease) or multiple (multiple foci of metastatic disease in the same site or multiple sites).
Information regarding brain involvement may be clinical or pathologic.
Code this field for brain metastasis even if the patient had neoadjuvant (preoperative) systemic therapy, unless it is determined to be disease progression.
Code brain involvement in this field for all solid tumors, Kaposi’s sarcoma, Lymphomas, Unknown primary site and Other and Ill-defined primary sites.
Code this field for Lymphomas of all sites for the histologies (9590-9699, 9702-9727, 9735, 9737-9738, 9811-9818, 9823, 8927, and 9737).
Assign the code that best describes whether the case has brain metastasis at diagnosis.
Use code 0 when the medical record:
Indicates no distant (discontinuous) metastases to the brain. Including:
A negative clinical or pathologic statement
Negative imaging reports
Mentions (discontinuous) metastasis but brain is not stated as the involved site.
Use code 1 when the medical record confirms:
The patient has distant (discontinuous) metastasis and the brain is mentioned as involved.
The patient is diagnosed with an unknown primary (C80.9) and brain is mentioned as a distant metastatic site.
Use code 8 (Not applicable) for the following site/histology combinations for which a code for distant metastasis is not clinically relevant:
ICD-O-3 Site |
ICD-O-3 Histology |
Description |
C000-C809 |
9740-9809, 9840-9992 |
Mast cell, histiocytosis, immunoproliferative, leukemias |
C000-C440, C442-C689, C691-C694, C698-C809 |
9820, 9826, 9831-9834, 9731, 9732, 9734 |
Other hematopietic neoplasm coded to any site except eyelid, conjunctiva, lacrimal gland, orbit, and eye overlapping and NOS |
Use code 9 when the patient is known to have distant metastasis but it cannot be determined whether the distant metastasis include brain.
Code |
Description |
0 |
None; no brain involvement |
1 |
Yes, distant brain metastasis |
8 |
Not Applicable |
9 |
Unknown whether brain is an involved metastatic site Not documented in patient record |